Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39]

Catalog number ET7108-68

Price for ET7108-68

Size / count 100 µL

About this product

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. GLI-3 (GLI family zinc finger 3), also known as GLI3FL (GLI3 full length protein), PHS, ACLS, GCPS, PAPA, PAPB, PAPA1 or PPDIV, is a 1,580 amino acid nuclear and cytoplasmic protein that acts as both a transcriptional activator and a repressor of the Sonic hedgehog (Shh) pathway. A member of the GLI C2H2-type zinc-finger protein family, GLI-3 is encoded by a gene that maps to human chromosome 7p14.1. Defects in the GLI-3 gene are the cause of a disorder known as Greig cephalo-poly-syndactyly syndrome (GCPS), which affects limb and craniofacial development.

Specifications

Catalog number: ET7108-68
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: ACLS antibody DNA binding protein antibody GCPS antibody Gli 3 antibody GLI family zinc finger 3 antibody GLI Kruppel family member GLI 3 antibody GLI Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) antibody GLI Kruppel family member GLI3 antibody GLI3 antibody GLI3 C-terminally truncated form antibody GLI3 form of 190 kDa antibody GLI3 form of 83 kDa antibody GLI3 full length protein antibody GLI3-190 antibody GLI3-83 antibody GLI3_HUMAN antibody GLI3FL antibody Glioma associated oncogene family zinc finger 3 antibody Oncogene GLI3 antibody PAP A antibody PAPA 1 antibody PAPA antibody PAPA1 antibody PAPB antibody PHS antibody PPD IV antibody PPDIV antibody Transcriptional activator GLI3 antibody Transcriptional repressor GLI3R antibody Zinc finger protein GLI 3 antibody Zinc finger protein GLI3 antibody
Abbreviation: GLI3-190, GLI3FL, GLI3-83, GLI3
Swiss Prot: P10071 Human
Cellular Locus: Cytoplasm. Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human Gli3 aa 1261-1580 / 1580.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell
Positive Control: PC-3M cell lysates.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 190 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39]?

The catalog number for Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39] is ET7108-68.

What sizes are available for Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39]?

Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39] is available in the following size(s): 100 µL.

Is Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39] in stock?

Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Gli3 Recombinant Rabbit Monoclonal Antibody [JG83-39] used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.