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Product details

Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40]

Catalog number ET7108-69

Price for ET7108-69

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Size / count 100 µL

About this product

The process of metabolizing purines to a common molecule known as xanthine is an essential process for the proper shuttling of uric acid. Xanthine oxidase is a flavoprotein enzyme that coordinates molybdenum and utilizes NAD+ as an electron acceptor to catalyze the oxidation of hypoxanthine to xanthine and then to uric acid. The predominant form of this enzyme is xanthine dehydrogenase, which is a homodimer that can be converted to xanthine oxidase by sulfhydryl oxidation or proteolytic modification. Xanthine oxidase is present in species ranging from bacteria to human and is ubiquitously expressed in mammalian tissues. In the oxidase form, this enzyme is coupled to the generation of free radicals. Individuals showing marked elevation of serum xanthine oxidase is suggestive of chronic liver disease and cholestasis, which is a condition defined by hepatic obstruction. Hepatic obstruction causes bile salts, the bile pigment bilirubin, and fats to accumulate in the blood stream instead of being eliminated normally. The clinical consequences of defects in xanthine oxidase range from mild to severe and even contribute to fatal disorders.

Specifications

Catalog number
ET7108-69
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Xanthine dehydrogenase antibody Xanthine dehydrogenase/oxidase antibody Xanthine oxidase antibody Xanthine oxidoreductase antibody XD antibody XDH antibody XDH_HUMAN antibody xdha antibody XO antibody xor antibody
Abbreviation
XD, XO, XOR, XDH, XDHA
Swiss Prot
P47989 Human, Q00519 Mouse, P22985 Rat
Cellular Locus
Cytoplasm. Peroxisome. Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Xanthine Oxidase aa 182-313 / 1333.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human kidney tissue lysates, rat liver tissue, human liver tissue, mouse liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
146 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40]?

The catalog number for Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40] is ET7108-69.

What sizes are available for Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40]?

Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40] is available in the following size(s): 100 µL.

Is Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40] in stock?

Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Xanthine Oxidase Recombinant Rabbit Monoclonal Antibody [JG38-40] used for?

The process of metabolizing purines to a common molecule known as xanthine is an essential process for the proper shuttling of uric acid. Xanthine oxidase is a flavoprotein enzyme that coordinates molybdenum and utilizes NAD+ as an electron acceptor to catalyze the oxidation of hypoxanthine to xanth

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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