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Product details

NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31]

Catalog number ET7108-72

Price for ET7108-72

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Size / count 100 µL

About this product

The heredity disease chronic granulomatous disease (CGF) has been linked to mutations in p47phox and p67phox. The cytosolic proteins p47phox and p67phox, also designated neutrophil cytosol factor 1 (NCF1) and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47phox and p67phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47phox and p67phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67phox has been shown to interact with the proline rich domain of p47phox, suggesting that p47phox may faciliate the transport of p67phox to the membrane.

Specifications

Catalog number
ET7108-72
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
67 kDa neutrophil oxidase factor antibody Chronic granulomatous disease autosomal 2 antibody FLJ93058 antibody NADPH oxidase activator 2 antibody NCF-2 antibody Ncf2 antibody NCF2_HUMAN antibody Neutrophil cytosol factor 2 antibody Neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2) antibody Neutrophil NADPH oxidase factor 2 antibody NOXA2 antibody P67 PHOX antibody p67-phox antibody p67phox antibody
Abbreviation
NCF-2, NCF2, NOXA2, P67PHOX
Swiss Prot
P19878 Human, O70145 Mouse, A7E3N2 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human NOXA2 aa 180-320 / 526.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IP
Positive Control
Rat spleen tissue lysates, rat spleen tissue, human spleen tissue, mouse spleen tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200 ;IP: 1:10-1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
60/47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31]?

The catalog number for NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31] is ET7108-72.

What sizes are available for NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31]?

NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31] is available in the following size(s): 100 µL.

Is NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31] in stock?

NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is NOXA2 Recombinant Rabbit Monoclonal Antibody [JG86-31] used for?

The heredity disease chronic granulomatous disease (CGF) has been linked to mutations in p47phox and p67phox. The cytosolic proteins p47phox and p67phox, also designated neutrophil cytosol factor 1 (NCF1) and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase i

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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