Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63] — image 1 of 3

Product details

Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63]

Catalog number ET7108-73

Price for ET7108-73

Size / count 100 µL

About this product

NudE-like protein (Ndel1) is expressed in the testis, brain, heart, hypothalamus, liver, lung, spleen, and stomach, specifically in the interphase centrosome and mitotic spindle. It positively regulates minus-end directed dynein. Evidence suggests that Ndel1 interacts with LIS1 to sustain the function of dynein, thereby impacting microtubule organization, nuclear translocation, and neuronal positioning. Ndel1 is phosphorylated during mitosis and seems to tether dynactin and dynein to the mother centriole for microtubule anchoring. Loss of function of Ndel1 in the developing neocortex impairs neuronal positioning and uncouples the centrosome and nucleus. Ndel1 may also impair mitochondrial transport or function, initiating a cascade of events culminating in psychiatric illness such as lissencephaly and schizophrenia.

Specifications

Catalog number: ET7108-73
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: A. nidulans antibody DKFZp451M0318 antibody ENDOOLIGOPEPTIDASE A antibody EOPA antibody MITAP 1 antibody MITAP1 antibody Mitosin associated protein 1 antibody Mitosin associated protein MITAP1 antibody Mitosin-associated protein 1 antibody Ndel 1 antibody NDEL1 antibody NDEL1_HUMAN antibody Nuclear distribution gene E like homolog 1 antibody Nuclear distribution protein nudE like 1 antibody Nuclear distribution protein nudE-like 1 antibody NUDE like protein antibody NudE nuclear distribution gene E homolog like 1 A. nidulans antibody NudE nuclear distribution gene E homolog like 1 antibody NUDEL antibody Protein Nudel antibody
Abbreviation: Protein Nudel, NDEL1, EOPA, MITAP1, NUDEL
Swiss Prot: Q9GZM8 Human, Q9ERR1 Mouse, Q78PB6 Rat
Cellular Locus: Cytoskeleton.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Nudel aa 1-49 / 345.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Rat brain tissue lysates, human liver cancer tissue, human small intestine tissue, human uterus tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 38 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63]?

The catalog number for Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63] is ET7108-73.

What sizes are available for Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63]?

Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63] is available in the following size(s): 100 µL.

Is Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63] in stock?

Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Nudel Recombinant Rabbit Monoclonal Antibody [JG38-63] used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.