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Product details

Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66]

Catalog number ET7108-74

Price for ET7108-74

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Size / count 100 µL

About this product

Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind Actin filaments and function to modulate Actin-Myosin interaction and stabilize Actin filament structure. Tropomyosin α is encoded by the TPM1 gene, which maps to human chromosome 15q22.1 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Tropomyosin β is encoded by the TPM2 gene, which maps to human chromosome 9p13.3 and undergoes alternative splicing to generate three isoforms, including skeletal muscle (isoform 1), non-muscle/fibroblast TM36/epithelial TMe1 (isoform 2) and non-muscle (isoform 3). Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with Actin filaments may increase the rigidity of Actin filaments. Tropomyosin also interacts with Caldesmon to regulate smooth muscle contraction.

Specifications

Catalog number
ET7108-74
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AA986836 antibody AI854628 antibody Alpha tropomyosin antibody alpha-TM antibody Alpha-tropomyosin antibody C15orf13 antibody cardiomyopathy, hypertrophic 3 antibody CMD1Y antibody CMH3 antibody HTM alpha antibody HTM-alpha antibody OTTHUMP00000163688 antibody sarcomeric tropomyosin kappa antibody TM2 antibody Tmpa antibody TMSA antibody Tpm-1 antibody TPM1 antibody TPM1_HUMAN antibody tropomyosin 1 (alpha) antibody tropomyosin 1 (alpha) isoform 1 antibody tropomyosin 1 (alpha) isoform 2 antibody tropomyosin 1 (alpha) isoform 3 antibody tropomyosin 1 (alpha) isoform 4 antibody tropomyosin 1 (alpha) isoform 5 antibody tropomyosin 1 (alpha) isoform 6 antibody tropomyosin 1 (alpha) isoform 7 antibody Tropomyosin 1 antibody Tropomyosin alpha 1 chain antibody Tropomyosin alpha-1 chain antibody Tropomyosin, skeletal muscle alpha antibody Tropomyosin-1 antibody
Abbreviation
TPM1, C15orf13, TMSA
Swiss Prot
P09493 Human, P58771 Mouse, P04692 Rat
Cellular Locus
Cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Tropomyosin 1 aa 168-284 / 284.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Rat heart tissue lysate, mouse heart tissue lysate, rat smooth muscle tissue, human heart tissue, mouse skeletal muscle tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
33 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66]?

The catalog number for Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66] is ET7108-74.

What sizes are available for Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66]?

Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66] is available in the following size(s): 100 µL.

Is Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66] in stock?

Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tropomyosin 1 Recombinant Rabbit Monoclonal Antibody [JG38-66] used for?

Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind Actin filaments and function to modulate Actin-Myosin interaction and stabilize Actin filament structure. Tropomyosin α is encoded by the TPM1 gene

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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