• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81]

Catalog number ET7108-82

Price for ET7108-82

Sign In for Pricing

Size / count 100 µL

About this product

BUB3 (budding uninhibited by benzimidazoles 3 homolog), also known as BUB3L or hBUB3, is a conserved component of the mitotic spindle assembly complex (MCC). It contains five WD repeat domains and forms cell cycle constitutive complexes with BUB1 and BUBR1. BUB3 is essential for the kinetochore localization of BUB1 and BUBR1. As a component of the MCC, BUB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. The spindle checkpoint pathway functions to postpone the initiation of anaphase until chromosomes are properly attached to the spindle. This acts to ensure accurate chromosome segregation. In addition, BUB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments. BUB3 is also thought to bind Tctex1L (or DYNLT3), a dynein light chain.

Specifications

Catalog number
ET7108-82
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Aa2-050 antibody AU019800 antibody AU021329 antibody AU043350 antibody AW146323 antibody BUB 3 antibody BUB 3L antibody BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog antibody bub3 antibody BUB3 budding uninhibited by benzimidazoles 3 homolog antibody BUB3 mitotic checkpoint protein antibody BUB3_HUMAN antibody BUB3L antibody Budding uninhibited by benomyl antibody Budding uninhibited by benzimidazoles 3 antibody Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) antibody Budding uninhibited by benzimidazoles 3 homolog (yeast) antibody Budding uninhibited by benzimidazoles 3 homolog antibody Budding uninhibited by benzimidazoles 3, S. cerevisiae, homolog of antibody C78067 antibody hBUB3 antibody Mitotic checkpoint component antibody Mitotic checkpoint protein bub3 antibody OTTHUMP00000020679 antibody OTTHUMP00000020680 antibody WD repeat type I transmembrane protein A72.5 antibody
Abbreviation
BUB3
Swiss Prot
O43684 Human, Q9WVA3 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Bub3 aa 2-50 / 328.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IP, IHC-P, FC
Positive Control
A549, HL-60, A431, rat colon tissue lysate, LOVO, rat testis tissue, human thyroid gland tissue, human colon cancer tissue, mouse fallopian tissue, PC-3M.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;IP: 1:10-1:50;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81]?

The catalog number for Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81] is ET7108-82.

What sizes are available for Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81]?

Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81] is available in the following size(s): 100 µL.

Is Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81] in stock?

Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Bub3 Recombinant Rabbit Monoclonal Antibody [JG38-81] used for?

BUB3 (budding uninhibited by benzimidazoles 3 homolog), also known as BUB3L or hBUB3, is a conserved component of the mitotic spindle assembly complex (MCC). It contains five WD repeat domains and forms cell cycle constitutive complexes with BUB1 and BUBR1. BUB3 is essential for the kinetochore loca

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

You Might Also Like
Von Willebrand Factor (3E2D10), CF647 conjugate, 0.1mg/mL
Von Willebrand Factor (3E2D10), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470633-100
CD104 (UM-A9), CF568 conjugate, 0.1mg/mL
CD104 (UM-A9), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680449-100
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF640R conjugate, 0.1mg/mL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400630-100
MART-1 / Melan-A (M2-7C10), CF647 conjugate, 0.1mg/mL
MART-1 / Melan-A (M2-7C10), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470009-500
CD53 (161-2), CF594 conjugate, 0.1mg/mL
CD53 (161-2), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940324-500
Myogenin (F5D), CF640R conjugate, 0.1mg/mL
Myogenin (F5D), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400632-100
P27 / KIP1 (SX53G8), CF647 conjugate, 0.1mg/mL
P27 / KIP1 (SX53G8), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470669-500