p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30] — image 1 of 3

Product details

p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30]

Catalog number ET7108-85

Price for ET7108-85

Size / count 100 µL

About this product

Chromatin assembly factor-1 (CAF-1) is a multisubunit protein complex that comprises three polypeptide subunits known as p150, p60, and p48. CAF-1 is a nucleosome assembly factor that deposits newly synthesized and acetylated histones H3/H4 into nascent chromatin during DNA replication. The p150 subunit of CAF-1 also supports the maintenance of heterochromatin, which requires the synthesis of both new histones and heterochromatin proteins and their orderly assembly during DNA replication. Heterochromatin is characterized as densely coiled chromatin that generally replicates late during S phase, has a low gene density, and contains large blocks of repetitive DNA that is relatively inaccessible to DNA-modifying reagents. In late S phase, p150 directly associates with heterochromatin associated proteins 1 (HP1α, HP1β and HP1γ). As cells prepare for mitosis, CAF-1 p150 and some HP1 progressively dissociate from heterochromatin, coinciding with the phosphorylation of histone H3. The HP1 proteins reassociate with chromatin at the end of mitosis, as histone H3 is dephosphorylated.

Specifications

Catalog number: ET7108-85
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CAF 1 subunit B antibody CAF 1A antibody CAF I 60 kDa subunit antibody CAF IP60 antibody CAF-1 antibody CAF-1 subunit B antibody CAF-I 60 kDa subunit antibody CAF-I p60 antibody CAF1 antibody CAF1A antibody CAF1B_HUMAN antibody CAF1P60 antibody CHAF 1B antibody CHAF1B antibody Chromatin assembly factor 1 subunit B antibody Chromatin assembly factor I antibody Chromatin assembly factor I p60 subunit antibody Human chromatin assembly factor-I p60 subunit antibody M phase phosphoprotein 7 antibody M-phase phosphoprotein 7 antibody MPHOSPH7 antibody MPP 7 antibody MPP7 antibody p60 subunit antibody
Abbreviation: CAF-1 subunit B, CAF-I 60 kDa subunit, CAF-I p60, CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Swiss Prot: Q13112 Human
Cellular Locus: Cytoplasm. Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human p60 CAF1 aa 419-559 / 559.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IP, IHC-P, FC
Positive Control: SiHa, K562, A431, 293T, human tonsil tissue, human appendix tissue, human colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;IP: 1:10-1:50;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 61 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30]?

The catalog number for p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30] is ET7108-85.

What sizes are available for p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30]?

p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30] is available in the following size(s): 100 µL.

Is p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30] in stock?

p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30] is currently made to order / not held in immediate stock. Contact us for lead time.

What is p60 CAF1 Recombinant Rabbit Monoclonal Antibody [JG92-30] used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.