ADAMTS13 Recombinant Rabbit Monoclonal Antibody [JG39-21]

About this product

ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)—also known as von Willebrand factor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. Glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2- (S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL.

Specifications

Catalog number

ET7108-86

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

A disintegrin and metalloproteinase with thrombospondin motifs 13 antibody A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 13 antibody A disintegrin like and metalloprotease with thrombospondin type 1 motif 13 antibody ADAM metallopeptidase with thrombospondin type 1 motif 13 antibody ADAM TS antibody ADAM-TS 13 antibody ADAM-TS13 antibody ADAMTS 13 antibody ADAMTS-13 antibody ADAMTS13 antibody ADAMTS13 protein antibody ATS13_HUMAN antibody C9orf8 antibody TTP antibody Von Willebrand factor cleaving protease antibody von Willebrand factor-cleaving protease antibody vWF cleaving protease antibody vWF CP antibody vWF-cleaving protease antibody vWF-CP antibody vWFCP antibody

Abbreviation

ADAM-TS 13, ADAM-TS13, ADAMTS-13, vWF-CP, vWF-cleaving protease, ADAMTS13, C9orf8

Swiss Prot

Q76LX8 Human,

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Synthetic peptide within Human ADAMTS13 aa 71-124 / 1,427.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

SiHa cell lysate, PC-3M cell lysate, A549 cell lysate, human kidney tissue, rat kidney tissue, human liver tissue, human colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:200-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size 154 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes