COMT Recombinant Rabbit Monoclonal Antibody [JG39-48] — image 1 of 2

Product details

COMT Recombinant Rabbit Monoclonal Antibody [JG39-48]

Catalog number ET7108-89

Price for ET7108-89

Size / count 100 µL

About this product

Catechol-O-methyltransferase (COMT) plays a crucial role in the regulation of central dopaminergic systems by catalyzing the inactivation of catechol-amines. It is widely distributed in most tissues in soluble and membrane-bound forms. COMT-mediated methylation metabolism of catecholamine neurotransmitters is a first-line detoxification pathway. A Val158Met polymorphism of the COMT gene affects activity of the enzyme and influences performance and efficiency of the prefrontal cortex of the brain. Sequential conversion of estradiol to methoxyestradiol by COMT, contributes to the antimitogenic effects of estradiol on vascular smooth muscle cell growth via estrogen receptor-independent mechanisms.

Specifications

Catalog number: ET7108-89
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Catechol O methyltransferase antibody Catechol O-methyltransferase antibody COMT antibody COMT_HUMAN antibody EC 2.1.1.6 antibody
Abbreviation: COMT
Swiss Prot: P21964 Human, O88587 Mouse, P22734 Rat
Cellular Locus: Cell membrane. Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within COMT aa 11-107 / 271.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: MCF-7, rat testis tissue lysate, mouse testis tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IHC-P: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 24 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for COMT Recombinant Rabbit Monoclonal Antibody [JG39-48]?

The catalog number for COMT Recombinant Rabbit Monoclonal Antibody [JG39-48] is ET7108-89.

What sizes are available for COMT Recombinant Rabbit Monoclonal Antibody [JG39-48]?

COMT Recombinant Rabbit Monoclonal Antibody [JG39-48] is available in the following size(s): 100 µL.

Is COMT Recombinant Rabbit Monoclonal Antibody [JG39-48] in stock?

COMT Recombinant Rabbit Monoclonal Antibody [JG39-48] is currently made to order / not held in immediate stock. Contact us for lead time.

What is COMT Recombinant Rabbit Monoclonal Antibody [JG39-48] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.