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Product details

CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73]

Catalog number ET7108-96

Price for ET7108-96

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Size / count 100 µL

About this product

CtBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T-cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of δEF1, a cellular zinc finger-homeodomain protein, and thereby enhances δEF1 induced transcriptional silencing. In addition, CtBP complexes with CtIP, a protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. CtIP/CtBP binding to BRCA1 inhibits the transactivation of the p21 promoter, and it is critical for regulating p21 transcription in response to DNA damage.

Specifications

Catalog number
ET7108-96
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
BARS antibody brefeldin A- ribosylated substrate antibody C terminal binding protein 1 antibody C-terminal-binding protein 1 antibody CTBP antibody CtBP1 antibody CTBP1_HUMAN antibody MGC104684 antibody
Abbreviation
CtBP1, CTBP1, CTBP
Swiss Prot
Q13363 Human, Q9Z2F5 Rat
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human CtBP1 aa 261-440 / 440.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, IF-Tissue, IP
Positive Control
PC-3M cell lysates, A549, human colon tissue, rat kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:100 ;IP: 1:10-1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73]?

The catalog number for CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73] is ET7108-96.

What sizes are available for CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73]?

CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73] is available in the following size(s): 100 µL.

Is CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73] in stock?

CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CtBP1 Recombinant Rabbit Monoclonal Antibody [JG39-73] used for?

CtBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PL

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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