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Product details

Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79]

Catalog number ET7108-97

Price for ET7108-97

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Size / count 100 µL

About this product

Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.

Specifications

Catalog number
ET7108-97
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
A930035J23Rik antibody AI047573 antibody AL024412 antibody Amp2 antibody AU014659, antibody EIF 2 associated p67 homolog antibody EIF-2-associated p67 antibody Initiation factor 2 associated 67 kDa glycoprotein antibody Initiation factor 2-associated 67 kDa glycoprotein antibody MAP 2 antibody MAP2 antibody MAP2_HUMAN antibody MetAP 2 antibody Metap2 antibody Methionine aminopeptidase 2 antibody Methionyl aminopeptidase 2 antibody MGC102452 antibody MGC127390 antibody MGC53792 antibody MNPEP antibody p67 antibody p67eIF2 antibody Peptidase M antibody Peptidase M2 antibody
Abbreviation
MAP 2, MetAP 2, p67, p67eIF2, METAP2, MNPEP, P67EIF2
Swiss Prot
P50579 Human, O08663 Mouse, P38062 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Methionine Aminopeptidase 2 aa 340-478 / 478.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
Daudi cell lysate, K562 cell lysate, mouse thymus tissue lysate, mouse kidney tissue lysate, LOVO, PC-3M, SH-SY5Y, rat seminal vesicle tissue, human tonsil tissue, human prostate carcinoma tissue, human kidney tissue, mouse testis tissue, Daudi.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size 53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79]?

The catalog number for Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79] is ET7108-97.

What sizes are available for Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79]?

Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79] is available in the following size(s): 100 µL.

Is Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79] in stock?

Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Methionine Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody [JG39-79] used for?

Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes pos

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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