SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06] — image 1 of 3

Product details

SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06]

Catalog number ET7109-02

Price for ET7109-02

Size / count 100 µL

About this product

Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor. SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.

Specifications

Catalog number: ET7109-02
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: HsT17379 antibody MGC8664 antibody SNX 1 antibody SNX 1a antibody Snx1 antibody SNX1_HUMAN antibody SNX1A antibody Sorting nexin 1 antibody Sorting nexin 1A antibody Sorting nexin-1 antibody Vps5 antibody
Abbreviation: SNX1
Swiss Prot: Q13596 Human, Q99N27 Rat
Cellular Locus: Endosome. Golgi apparatus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human SNX1 aa 1-140 / 522.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control: Human skin tissue lysates, A549, SH-SY5Y, SiHa, rat epididymis tissue, human colon tissue, human breast carcinoma tissue, Hela.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 63 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06]?

The catalog number for SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06] is ET7109-02.

What sizes are available for SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06]?

SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06] is available in the following size(s): 100 µL.

Is SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06] in stock?

SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SNX1 Recombinant Rabbit Monoclonal Antibody [JG40-06] used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.