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Product details

CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36]

Catalog number ET7109-05

Price for ET7109-05

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Size / count 100 µL

About this product

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endo-genous and xenobiotic compounds. P450 enzymes can be classified, based on their sequence similarities, into distinct subfamilies, which include CYP1A and CYP2A. Other P450 family members include CYP19, also designated aromatase (P450arom), which catalyzes the conversion of C19 steroids to estrogens in various tissues, including placenta, gonads, adipose tissue, skin and brain. CYP19 expression is controlled by hormonally regulated promoters in different tissues and increased aromatase activity is associated with familial gynecomastia. Also, a polymorphic allele of CYP19 (repeat (TTTA)12) is present in a majority of breast cancer patients. P450 cholesterol 7a-hydroxylase, CYP7A1, is the rate limiting enzyme of bile acid synthesis in the liver, and its expression is mediated by the bile acid receptor FXR. CYP27A1 catalyzes vitamin D3 25-hydroxylation and is localized to the mitochondria in kidney and liver.

Specifications

Catalog number
ET7109-05
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
12-alpha-triol 27-hydroxylase antibody 5-beta-cholestane-3-alpha antibody 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase antibody 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase antibody 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase antibody 7-alpha antibody Cholestanetriol 26 monooxygenase antibody CP27 antibody CP27A_HUMAN antibody CTX antibody CYP antibody CYP27 antibody CYP27A1 antibody Cytochrome P 450C27/25 antibody Cytochrome P-450C27/25 antibody Cytochrome P450 27 antibody Cytochrome P450 27 mitochondrial antibody Cytochrome P450 family 27 subfamily A member 1 antibody Cytochrome P450 family 27 subfamily A polypeptide 1 antibody Cytochrome P450 subfamily XXVIIA (steroid 27-hydroxylase cerebrotendinous xanthomatosis) polypeptide 1 antibody mitochondrial antibody Sterol 26 hydroxylase antibody Sterol 26 hydroxylase mitochondrial antibody Sterol 26-hydroxylase antibody Sterol 27 hydroxylase antibody Sterol 27-hydroxylase antibody Vitamin D (3) 25 hydroxylase antibody Vitamin D (3) 25-hydroxylase antibody
Abbreviation
Cytochrome P-450C27/25, Cytochrome P450 27, CYP27A1, CYP27
Swiss Prot
Q02318 Human, Q9DBG1 Mouse, P17178 Rat
Cellular Locus
Mitochondrion membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human CYP27A1 aa 400-531 / 531.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Rat heart tissue lysate, mouse liver tissue lysate, human liver tissue lysate, HepG2, LOVO, human liver carcinoma tissue, human kidney tissue, human small intestine tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
60 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36]?

The catalog number for CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36] is ET7109-05.

What sizes are available for CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36]?

CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36] is available in the following size(s): 100 µL.

Is CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36] in stock?

CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CYP27A1 Recombinant Rabbit Monoclonal Antibody [JG40-36] used for?

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endo-genous and xenobiotic compounds. P450 enzymes can be classified, based on their sequence similarities, into distinct subfamilies, which include CYP1A and CYP2A. Other P450 family mem

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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