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Product details

Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47]

Catalog number ET7109-09

Price for ET7109-09

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Size / count 100 µL

About this product

Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFS4 (NADH dehydrogenase (ubiquinone) Fe-S protein 4), also known as AQDQ or CI-18 (Complex I-18kDa protein), belongs to the Complex I NDUFS4 subunit family. NDUFS4 localizes to the matrix side of the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. Mutations in the gene encoding NDUFS4 can result in Complex I mitochondrial respiratory chain deficiency. Patients with this deficiency may exhibit cardiomyopathy, myopathy, liver failure and neurological disorders.

Specifications

Catalog number
ET7109-09
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AQDQ antibody CI 18 antibody CI 18 kDa antibody CI AQDQ antibody CI-18 kDa antibody CI-AQDQ antibody Complex I 18 kDa antibody Complex I AQDQ antibody Complex I-18 kDa antibody Complex I-AQDQ antibody mitochondrial antibody mitochondrial respiratory chain complex I (18 KD subunit) antibody NADH coenzyme Q reductase antibody NADH dehydrogenase (ubiquinone) Fe S protein 4 18kDa antibody NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 antibody NADH dehydrogenase antibody NADH ubiquinone oxidoreductase 18 kDa subunit antibody NADH-ubiquinone oxidoreductase 18 kDa subunit antibody NDUFS4 antibody NDUS4_HUMAN antibody
Abbreviation
CI-18 kDa, CI-AQDQ, NDUFS4
Swiss Prot
O43181 Human, Q5XIF3 Rat
Cellular Locus
Mitochondrion.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Ndufs4 aa 1-140 / 175.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IP
Positive Control
Rat heart tissue lysate, rat kidney tissue, human small intestine tissue, SH-SY-5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: 1:10-1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 20 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47]?

The catalog number for Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47] is ET7109-09.

What sizes are available for Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47]?

Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47] is available in the following size(s): 100 µL.

Is Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47] in stock?

Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Ndufs4 Recombinant Rabbit Monoclonal Antibody [JE40-47] used for?

Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an e

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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