DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59] — image 1 of 3

Product details

DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59]

Catalog number ET7109-11

Price for ET7109-11

Size / count 100 µL

About this product

Dia 1, also known as DIAPH1 (diaphanous homolog 1) or DRF1, a mammalian homolog of the Drosophila diaphanous gene, belongs to a family of formin homology (FH) proteins which are characterized by having tandemly aligned FH1 (formin homology 1) and FH2 (formin homology 2) domains in their carboxy terminal regions. Dia 1 contains a DAD (diaphanous autoregulatory) domain, which is involved in the elongation of actin filaments, and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain, which interacts with the DAD domain via autoinhibitory interactions to regulate the activation of Dia 1. Dia 1 is required for the assembly of F-actin structures, and regulates the polymerization and depolymerization of actin filaments. Localizing to the cell membrane, Dia 1 is expressed in a wide range of tissues, including brain, heart, lung and kidney. Defects to the gene encoding Dia 1 have been linked to deafness autosomal dominant type 1 (DFNA1), a disorder characterized by sensorineural hearing loss..

Specifications

Catalog number: ET7109-11
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: DIAPH1 antibody deafness, autosomal dominant 1 antibody DFNA1 antibody DIA1 antibody DIAP1 antibody DIAP1_HUMAN antibody DIAPH1 antibody Diaphanous homolog 1 (Drosophila) antibody diaphanous homolog 1 antibody Diaphanous related formin 1 antibody Diaphanous-related formin-1 antibody DRF1 antibody FLJ25265 antibody hDIA1 antibody LFHL1 antibody low frequency hearing loss 1 antibody p140DIA antibody Protein diaphanous homolog 1 antibody
Abbreviation: DRF1, DIAPH1, DIAP1
Swiss Prot: O60610 Human
Cellular Locus: Cytoskeleton. Plasma membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human DIAPH1 aa 1-50 / 1,272.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P
Positive Control: SiHa, LOVO, human liver cancer tissue, human colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:5,000-1:10,000;IF-Cell: 1:50;IHC-P: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 141 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59]?

The catalog number for DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59] is ET7109-11.

What sizes are available for DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59]?

DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59] is available in the following size(s): 100 µL.

Is DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59] in stock?

DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DIAPH1 Recombinant Rabbit Monoclonal Antibody [JE40-59] used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.