PGAM1 Recombinant Rabbit Monoclonal Antibody [JE40-67]

About this product

Members of the PGAM (phosphoglycerate mutase) family of proteins are important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism. They are responsible for catalyzing the transfer of phospho groups between the carbon atoms of phosphoglycerates. In mammals there are two types of PGAM isozymes: PGAM1 (also known as PGAMB) and PGAM2 (also known as PGAMA). In the cell, PGAM1 and PGAM2 exist as either homodimers or heterodimers and are responsible for the interconversion of 3-phosphoglycerate and 2-phosphoglycerate. PGAM2 homodimers are expressed in skeletal muscle, mature sperm cells and heart; PGAM1 homodimers are found in most other tissues; and PGAM1/PGAM2 heterodimers are found exclusively in the heart. PGAM4, also known as PGAM3, is a protein formerly considered to be specific to humans. Initially the PGAM4 gene was described as a pseudogene but it is now known to encode a functional protein at least 25 million years old. The gene encoding PGAM4 is believed to have originated by retrotransposition, with the original copy being the PGAM1 gene.

Specifications

Catalog number

ET7109-13

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

BPG dependent PGAM 1 antibody BPG dependent PGAM1 antibody BPG-dependent PGAM 1 antibody OTTHUMP00000059414 antibody PGAM 1 antibody PGAM A antibody PGAM B antibody PGAM-B antibody PGAM1 antibody PGAM1_HUMAN antibody PGAMA antibody PGAMB antibody Phosphoglycerate mutase 1 antibody Phosphoglycerate mutase 1 brain antibody Phosphoglycerate mutase A antibody Phosphoglycerate mutase A nonmuscle form antibody Phosphoglycerate mutase isozyme B antibody

Abbreviation

PGAM-B, PGAM1, PGAMA

Swiss Prot

P18669 Human, Q9DBJ1 Mouse, P25113 Rat

Cellular Locus

Cytosol. Extracellular region or secreted. Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human PGAM1 aa 1-103 / 254.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

A431, A549, rat brain tissue, mouse brain tissue, human liver tissue, Jurkat.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:100 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

29 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes