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Product details

MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97]

Catalog number ET7109-20

Price for ET7109-20

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Size / count 100 µL

About this product

Microtubule affinity-regulating kinase 2 (MARK2), also known as EMK1 (ELKL motif kinase 1) or Par1b, is a 788 amino acid protein that is a member of the protein kinase superfamily, MARK subfamily. Highly expressed in heart, brain, skeletal muscle and pancreas, MARK2 is essential for the asymmetric development of membrane domains around polarized epithelial cells. Activation of MARK2 by phosphorylation on Thr 208 allows the protein to modulate the building of a columnar versus a hepatic epithelial cell. MARK2 contains one KA1 (kinase-associated) domain, one protein kinase domain and one UBA domain. MARK2 is expressed as 14 isoforms produced by alternative splicing events. Some of these isoforms may function in graft rejection.

Specifications

Catalog number
ET7109-20
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ELKL motif kinase 1 antibody ELKL motif kinase antibody EMK-1 antibody EMK1 antibody MAP/microtubule affinity regulating kinase 2 antibody MAP/microtubule affinity-regulating kinase 2 antibody Mark2 antibody MARK2_HUMAN antibody MGC99619 antibody PAR 1 antibody Par 1b antibody PAR1 homolog antibody Par1b antibody Ser/Thr protein kinase PAR 1B antibody Serine/threonine protein kinase EMK antibody Serine/threonine protein kinase MARK2 antibody Serine/threonine-protein kinase MARK2 antibody
Abbreviation
EMK-1, Par-1b, Par1b, MARK2, EMK1
Swiss Prot
Q7KZI7 Human
Cellular Locus
Cell membrane. Cytoplasm. Cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human MARK2 aa 661-789 / 789.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
MCF-7, SK-Br-3, human appendix tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 88 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97]?

The catalog number for MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97] is ET7109-20.

What sizes are available for MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97]?

MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97] is available in the following size(s): 100 µL.

Is MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97] in stock?

MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MARK2 Recombinant Rabbit Monoclonal Antibody [JE40-97] used for?

Microtubule affinity-regulating kinase 2 (MARK2), also known as EMK1 (ELKL motif kinase 1) or Par1b, is a 788 amino acid protein that is a member of the protein kinase superfamily, MARK subfamily. Highly expressed in heart, brain, skeletal muscle and pancreas, MARK2 is essential for the asymmetric d

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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