Product details
Catalog number ET7109-25
Price for ET7109-25
Size / count 100 µL
Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. It interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD. MAFbx is specifically expressed in cardiac and skeletal muscle.
The catalog number for Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] is ET7109-25.
Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] is available in the following size(s): 100 µL.
Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] is currently made to order / not held in immediate stock. Contact us for lead time.
Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recogniz
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