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Product details

Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27]

Catalog number ET7109-25

Price for ET7109-25

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Size / count 100 µL

About this product

Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. It interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD. MAFbx is specifically expressed in cardiac and skeletal muscle.

Specifications

Catalog number
ET7109-25
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
4833442G10Rik antibody AI430017 antibody Atrogin 1 antibody Atrogin-1 antibody ATROGIN1 antibody Atrophy gene 1 antibody F box only protein 32 antibody F-box only protein 32 antibody F-box protein 32 antibody FBX32_HUMAN antibody fbxo25 antibody FBXO32 antibody FLJ32424 antibody MAFbx antibody MGC108443 antibody MGC137646 antibody MGC33610 antibody Muscle atrophy F box antibody Muscle atrophy F box protein antibody Muscle atrophy F-box protein antibody
Abbreviation
MAFbx, FBXO32
Swiss Prot
Q969P5 Human, Q9CPU7 Mouse, Q91Z62 Rat
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Fbx32 aa 1-160 / 355.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell
Positive Control
Mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, A431, L6.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27]?

The catalog number for Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] is ET7109-25.

What sizes are available for Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27]?

Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] is available in the following size(s): 100 µL.

Is Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] in stock?

Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Fbx32 Recombinant Rabbit Monoclonal Antibody [JE41-27] used for?

Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recogniz

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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