PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28] — image 1 of 3

Product details

PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28]

Catalog number ET7109-26

Price for ET7109-26

Size / count 100 µL

About this product

Four proteins comprise the gamma-secretase complex: presenilin, nicastrin, aph-1, and PEN-2. Together, these proteins mediate cell surface signaling pathways for a variety of type I membrane proteins, notably amyloid-beta precursor protein, a protein implicated in the development of Alzheimer's disease, via intramembrane proteolysis. The proteins assemble into a proteolytically active complex in the golgi/trans-golgi network (TGN) compartments. Assembly leads to autocleavage of presenilin into two subunits to create the active site of gamma-secretase, an important step in understanding the mechanisms involved in the etiology and possible treatment of Alzheimer's disease.

Specifications

Catalog number: ET7109-26
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Gamma secretase subunit PEN 2 antibody Gamma Secretase Subunit PEN2 antibody Gamma-secretase subunit PEN-2 antibody Hematopoietic stem/progenitor cells protein MDS033 antibody MDS033 antibody MSTP064 antibody PEN 2 antibody PEN2_HUMAN antibody Presenilin Enhancer 2 antibody Presenilin enhancer 2 homolog antibody Presenilin enhancer protein 2 antibody PSEN2 antibody psenen antibody
Abbreviation: PSENEN, PEN2, MDS033
Swiss Prot: Q9NZ42 Human, Q9CQR7 Mouse, O88777 Rat
Cellular Locus: Cell membrane. Endoplasmic reticulum. Golgi apparatus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human PEN2 aa 1-101 / 101.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC, IHC-Fr, IF-Tissue
Positive Control: Mouse spleen tissue lysates, A549, SH-SY5Y, human lung carcinoma tissue, human kidney tissue, rat cerebellum tissue, mouse testis tissue, human tonsil tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:100 ;IHC-Fr: 1:100 ;IF-Tissue: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 12 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28]?

The catalog number for PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28] is ET7109-26.

What sizes are available for PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28]?

PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28] is available in the following size(s): 100 µL.

Is PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28] in stock?

PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PEN2 Recombinant Rabbit Monoclonal Antibody [JE41-28] used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.