CLASP1 Recombinant Rabbit Monoclonal Antibody [JE43-19]

About this product

Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Specifications

Catalog number

ET7109-31

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

1700030C23Rik antibody 5730583A19Rik antibody B130045P17Rik antibody CLAP1_HUMAN antibody clasp1 antibody CLIP associating protein 1 antibody CLIP associating protein CLASP1 antibody CLIP-associating protein 1 antibody Cytoplasmic linker associated protein 1 antibody Cytoplasmic linker-associated protein 1 antibody DKFZp686D1968 antibody DKFZp686H2039 antibody FLJ33821 antibody FLJ41222 antibody hOrbit1 antibody KIAA0622 antibody MAST1 antibody MGC131895 antibody mKIAA0622 antibody Multiple asters 1 antibody Multiple asters homolog 1 antibody Protein Orbit homolog 1 antibody

Abbreviation

hOrbit1, CLASP1, KIAA0622, MAST1

Swiss Prot

Q7Z460 Human, Q80TV8 Mouse,

Cellular Locus

Cytoskeleton, Golgi apparatus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human CLASP1 aa 1-50 / 1,538.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

HepG2 cell lysate, Daudi cell lysate, SH-SY-5Y, SiHa, rat kidney tissue, human stomach tissue, human small intestine tissue, mouse colon tissue.

Concentration

1 mg/mL

Dilution

WB:1:500-1:2,000 ;IF-Cell:1:50-1:200 ;IF-Tissue:1:50-1:200 ;IHC-P:1:50-1:1,000 ;FC:1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 169 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes