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Product details

SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44]

Catalog number ET7109-47

Price for ET7109-47

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Size / count 100 µL

About this product

Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244). RNA-binding is semi-sequence specific.

Specifications

Catalog number
ET7109-47
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
arginine/serine-rich 3 antibody Pre mRNA splicing factor SRP20 antibody Pre-mRNA-splicing factor SRP20 antibody Serine/arginine-rich splicing factor 3 antibody Splicing factor antibody Splicing factor arginine/serine rich 20 kD antibody Splicing factor arginine/serine rich 3 antibody SRp20 antibody SRSF3 antibody SRSF3_HUMAN antibody X16 antibody
Abbreviation
SRSF3, SFRS3, SRP20
Swiss Prot
P84103 Human, P84104 Mouse,
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human SFRS3 aa 34-83 / 164.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Mouse testis tissue lysate, rat brain tissue lysate, A431 cell lysate, SH-SY-5Y cell lysate, SiHa cell lysate, 293 cell lysate, Hela cell lysate, HepG2 cell lysate, A549 cell lysate, rat brain tissue, human colon tissue, human breast cancer tissue, human kidney tissue, mouse testis tissue, MG-63.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000;IF-Cell:1:50;IHC-P:1:100-1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 19 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44]?

The catalog number for SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44] is ET7109-47.

What sizes are available for SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44]?

SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44] is available in the following size(s): 100 µL.

Is SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44] in stock?

SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SFRS3 Recombinant Rabbit Monoclonal Antibody [JE46-44] used for?

Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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