NDUFAF1 Recombinant Rabbit Monoclonal Antibody [JE47-18]

About this product

This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. Part of the mitochondrial complex I assembly (MCIA) complex. The complex comprises at least TMEM126B, NDUFAF1, ECSIT, and ACAD9. Interacts with ECSIT. Interacts with ACAD9. At early stages of complex I assembly, it is found in intermediate subcomplexes that contain different subunits including NDUFB6, NDUFA6, NDUFA9, NDUFS3, NDUFS7, ND1, ND2 and ND3

Specifications

Catalog number

ET7109-54

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CGI 65 antibody CGI65 antibody CIA30 antibody CIA30_HUMAN antibody Complex I intermediate associated protein 30 antibody Complex I intermediate associated protein 30 mitochondrial antibody Complex I intermediate-associated protein 30, mitochondrial antibody NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 1 antibody NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1 antibody NADH:ubiquinone oxidoreductase complex assembly factor 1 antibody NDUFAF 1 antibody Ndufaf1 antibod

Abbreviation

NDUFAF1, CIA30

Swiss Prot

Q9Y375 Human

Cellular Locus

Mitochondrion.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human NDUFAF1 aa 1-190 / 327.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

K-562 cell lysate, HeLa cell lysate, Jurkat cell lysate, HEK-293 cell lysate, 293T, SKOV-3, human kidney tissue, human liver tissue, K-562.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 38 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes