COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48] — image 1 of 3

Product details

COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48]

Catalog number ET7109-60

Price for ET7109-60

Size / count 100 µL

About this product

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Specifications

Catalog number: ET7109-60
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Constitutive photomorphogenic homolog subunit 3 antibody COP 9 (constitutive photomorphogenic) subunit 3 antibody COP 9 complex homolog subunit 3 antibody COP 9 complex S3 antibody COP 9 complex subunit 3 antibody COP 9 constitutive photomorphogenic homolog subunit 3 antibody COP 9 homolog antibody COP 9 signalosome complex subunit 3 antibody COP 9 signalosome subunit 3 antibody COP 9 subunit 3 antibody COP9 (constitutive photomorphogenic) subunit 3 antibody COP9 complex homolog subunit 3 antibody COP9 complex S3 antibody COP9 complex subunit 3 antibody COP9 constitutive photomorphogenic homolog subunit 3 antibody COP9 homolog antibody COP9 signalosome complex subunit 3 antibody COP9 signalosome subunit 3 antibody COP9 subunit 3 antibody COPS 3 antibody cops3 antibody CSN 3 antibody CSN3 antibody CSN3_HUMAN antibody JAB 1 containing signalosome subunit 3 antibody JAB1 containing signalosome subunit 3 antibody JAB1-containing signalosome subunit 3 antibody SGN 3 antibody SGN3 antibody Signalosome subunit 3 antibody
Abbreviation: SGN3, Signalosome subunit 3, COPS3, CSN3
Swiss Prot: Q9UNS2 Human, O88543 Mouse, Q68FW9 Rat
Cellular Locus: Cytoplasm. Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human COPS3 / CSN3 aa 280-423 / 423.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Human skeletal muscle tissue, Rat bone marrow, A431, HCT116, rat heart tissue, human liver cancer tissue, human breast tissue, human pancreas tissue, mouse kidney tissue, mouse heart tissue, 293.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:1,000;IF-Cell:1:500-1:2,000;IHC-P:1:50-1:200;FC:1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48]?

The catalog number for COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48] is ET7109-60.

What sizes are available for COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48]?

COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48] is available in the following size(s): 100 µL.

Is COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48] in stock?

COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48] is currently made to order / not held in immediate stock. Contact us for lead time.

What is COPS3/CSN3 Recombinant Rabbit Monoclonal Antibody [JE47-48] used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.