ACADM Recombinant Rabbit Monoclonal Antibody [JE48-09]

About this product

ACADM (acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain) is a gene that provides instructions for making an enzyme called acyl-coenzyme A dehydrogenase that is important for breaking down (degrading) a certain group of fats called medium-chain fatty acids. These fatty acids are found in foods such as milk and certain oils, and they are also stored in the body's fat tissue. Medium-chain fatty acids are also produced when larger fatty acids are degraded. The acyl-coenzyme A dehydrogenase for medium-chain fatty acids (ACADM) enzyme is essential for converting these particular fatty acids to energy, especially during periods without food (fasting). The ACADM enzyme functions in mitochondria, the energy-producing centers within cells. It is found in the mitochondria of several types of tissues, particularly the liver. The LCAD enzyme catalyzes most of fatty acid beta-oxidation by forming a C2-C3 trans-double bond in the fatty acid. MCAD works on long-chain fatty acids, typically between C4 and C12-acylCoA. Fatty acid oxidation has proven to spare glucose in fasting conditions, and is also required for amino acid metabolism, which is essential for the maintenance of adequate glucose production. Furthermore, MCAD participates in fatty acid metabolism and PPAR signaling pathway.

Specifications

Catalog number

ET7109-74

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ACAD 1 antibody ACAD1 antibody Acadm antibody ACADM_HUMAN antibody Acyl coenzyme A dehydrogenase antibody Acyl coenzyme A dehydrogenase C 4 to C 12 straight chain antibody FLJ18227 antibody FLJ93013 antibody FLJ99884 antibody MCAD antibody MCADH antibody Medium chain acyl CoA dehydrogenase antibody Medium chain fatty acyl CoA dehydrogenase antibody Medium chain specific acyl CoA dehydrogenase antibody Medium chain specific acyl CoA dehydrogenase mitochondrial antibody Medium-chain specific acyl-CoA dehydrogenase antibody mitochondrial antibody

Abbreviation

MCAD, ACADM

Swiss Prot

P11310 Human, P45952 Mouse, P08503 Rat

Cellular Locus

Mitochondrion.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human ACADM aa 100-230 / 421.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

A549-si NT cell lysate, A549-si 商品名 cell lysate, HeLa cell lysate, HepG2 cell lysate, MC/9 cell lysate, L6 cell lysate, Mouse heart tissue lysate, human kidney tissue, mouse kidney tissue, rat kidney tissue, Hela, SiHa.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 46 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes