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![MAD3 Recombinant Rabbit Monoclonal Antibody [JE48-14] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82ada/imageurl/et7109-76.webp)
Product details
Catalog number ET7109-76
Price for ET7109-76
Size / count 100 µL
MXD3 is a member of the MXD family of basic-helix-loop-helix transcription factors that form heterodimers with the cofactor MAX, and were originally proposed as functional antagonists of MYC proteins in the MYC/MAX/MAD transcriptional network. While some MXD proteins are MYC antagonists by acting as transcriptional repressors to promote cell differentiation, MXD3 is an atypical member that plays a role in proliferation rather than differentiation. MXD3 promotes granule neuron precursor (GNP) proliferation through a Sonic Hedgehog-mediated pathway, it is expressed in a mouse model of medulloblastoma, and its knock-down (KD) reduced proliferation of the human medulloblastoma cell line DAOY.
The catalog number for MAD3 Recombinant Rabbit Monoclonal Antibody [JE48-14] is ET7109-76.
MAD3 Recombinant Rabbit Monoclonal Antibody [JE48-14] is available in the following size(s): 100 µL.
MAD3 Recombinant Rabbit Monoclonal Antibody [JE48-14] is currently made to order / not held in immediate stock. Contact us for lead time.
MXD3 is a member of the MXD family of basic-helix-loop-helix transcription factors that form heterodimers with the cofactor MAX, and were originally proposed as functional antagonists of MYC proteins in the MYC/MAX/MAD transcriptional network. While some MXD proteins are MYC antagonists by acting as
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
