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![CLSTN1 Recombinant Rabbit Monoclonal Antibody [JE48-81] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea823fa/imageurl/et7109-84.webp)
Product details
Catalog number ET7109-84
Price for ET7109-84
Size / count 100 µL
Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity).
The catalog number for CLSTN1 Recombinant Rabbit Monoclonal Antibody [JE48-81] is ET7109-84.
CLSTN1 Recombinant Rabbit Monoclonal Antibody [JE48-81] is available in the following size(s): 100 µL.
CLSTN1 Recombinant Rabbit Monoclonal Antibody [JE48-81] is currently made to order / not held in immediate stock. Contact us for lead time.
Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with AP
Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
