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![APRIL/TNFSF13 Recombinant Rabbit Monoclonal Antibody [JE49-07] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80e40/imageurl/et7109-89.webp)
Product details
Catalog number ET7109-89
Price for ET7109-89
Size / count 100 µL
A proliferation-inducing ligand (APRIL), also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI. The protein encoded by this gene is a member of the tumor necrosis factor ligand (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vivo experiments suggest an important role for APRIL in the long-term survival of plasma cells in the bone marrow. Mice deficient in APRIL have normal immune system development. However, APRIL-deficient mice have also been reported to possess a reduced ability to support plasma cell survival. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
The catalog number for APRIL/TNFSF13 Recombinant Rabbit Monoclonal Antibody [JE49-07] is ET7109-89.
APRIL/TNFSF13 Recombinant Rabbit Monoclonal Antibody [JE49-07] is available in the following size(s): 100 µL.
APRIL/TNFSF13 Recombinant Rabbit Monoclonal Antibody [JE49-07] is currently made to order / not held in immediate stock. Contact us for lead time.
A proliferation-inducing ligand (APRIL), also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI. The protein encoded by this gene is a member of the tumor necrosis factor ligand (TNF) ligand family.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.
