CD239 Recombinant Rabbit Monoclonal Antibody [JE51-07]

About this product

Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membrane glycoprotein that in humans is encoded by the BCAM gene. BCAM has also recently been designated CD239 (cluster of differentiation 239). Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu (a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. BCAM has been shown to interact with Laminin, alpha 5.

Specifications

Catalog number

ET7110-04

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Antigen identified by monoclonal antibody F8 antibody AU antibody Auberger B antigen antibody B CAM cell surface glycoprotein antibody B cell adhesion molecule antibody B-CAM cell surface glycoprotein antibody Basal cell adhesion molecule (Lu and Au blood groups) antibody Basal cell adhesion molecule (Lutheran blood group) antibody Basal cell adhesion molecule antibody Basal cell adhesion molecule Lu and Au blood groups antibody Basal cell adhesion molecule Lutheran blood group antibody Bcam antibody BCAM_HUMAN antibody CD239 antibody CD239 antigen antibody F8/G253 antigen antibody Glycoprotein 95kDa antibody LU antibody Lutheran antibody Lutheran antigen antibody Lutheran blood group (Auberger b antigen included) antibody Lutheran blood group Auberger b antigen included antibody Lutheran blood group glycoprotein antibody MSK19 antibody

Abbreviation

BCAM

Swiss Prot

P50895 Human

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human CD239 aa 579-628 / 628.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

A431 cell lysate, human kidney tissue, human placenta tissue, JAR.

Concentration

1 mg/mL

Dilution

WB:1:500-1:2,000 ;IHC-P:1:100-1:500 ;FC:1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 67 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes