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Product details

EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84]

Catalog number ET7110-08

Price for ET7110-08

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Size / count 100 µL

About this product

Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.

Specifications

Catalog number
ET7110-08
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Ankyrin repeat containing protein antibody Bat 8 antibody Bat8 antibody C6orf30 antibody DKFZp686H08213 antibody EHMT 2 antibody Ehmt2 antibody EHMT2_HUMAN antibody Euchromatic histone lysine methyltransferase 2 antibody Euchromatic histone lysine N methyltransferase 2 antibody Euchromatic histone-lysine N-methyltransferase 2 antibody FLJ35547 antibody G 9a antibody G9 a antibody G9a protein antibody G9A antibody G9A histone methyltransferase antibody GAT8 antibody H3 K9 HMTase 3 antibody H3-K9-HMTase 3 antibody Histone H3 K9 methyltransferase 3 antibody Histone H3 K9 methyltransferase3 antibody Histone H3-K9 methyltransferase 3 antibody Histone lysine N methyltransferase antibody Histone lysine N methyltransferase EHMT2 antibody Histone lysine N methyltransferase, H3 lysine 9 specific 3 antibody Histone lysine N methyltransferase, H3 lysine 9 specific3 antibody Histone-lysine N-methyltransferase EHMT2 antibody HLA B associated transcript 8 antibody HLA-B-associated transcript 8 antibody KMT 1C antibody KMT1 C antibody Lysine N methyltransferase 1C antibody Lysine N-methyltransferase 1C antibody NG 36 antibody NG36 antibody Protein G9a antibody
Abbreviation
EHMT2
Swiss Prot
Q96KQ7 Human
Cellular Locus
Nucleus, chromosome.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human G9A aa 1,060-1,210 / 1,210.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human colon carcinoma tissue, human breast carcinoma tissue, human stomach carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:50-1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 132 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84]?

The catalog number for EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84] is ET7110-08.

What sizes are available for EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84]?

EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84] is available in the following size(s): 100 µL.

Is EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84] in stock?

EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84] is currently made to order / not held in immediate stock. Contact us for lead time.

What is EHMT2 / G9A Recombinant Rabbit Monoclonal Antibody [JE50-84] used for?

Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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