NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72] — image 1 of 2

Product details

NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72]

Catalog number ET7110-15

Price for ET7110-15

Size / count 100 µL

About this product

Serine/threonine-protein kinase Nek6 is an enzyme that in humans is encoded by the NEK6 gene. The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform functions similar to those of NIMA. It is a protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.

Specifications

Catalog number: ET7110-15
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Highly similar to cell cycle protein kinase CDC5/MSD2 antibody NEK6 antibody NEK6_HUMAN antibody Never in mitosis A-related kinase 6 antibody NIMA (Never In Mitosis Gene A) Related Kinase 6 antibody NimA related protein kinase 6 antibody NimA-related protein kinase 6 antibody Protein kinase SID6 1512 antibody Protein kinase SID6-1512 antibody Putative serine threonine protein kinase antibody Serine/threonine protein kinase Nek6 antibody Serine/threonine-protein kinase Nek6 antibody SID6 1512 antibody SID61512 antibody
Abbreviation: NEK6
Swiss Prot: Q9HC98 Human
Cellular Locus: Cytoplasm, Cytoskeleton, Microtubule, Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human NEK6 aa 170-313 / 313.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: THP-1 cell lysate, Wild-type 293T whole cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 36 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72]?

The catalog number for NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72] is ET7110-15.

What sizes are available for NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72]?

NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72] is available in the following size(s): 100 µL.

Is NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72] in stock?

NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72] is currently made to order / not held in immediate stock. Contact us for lead time.

What is NEK6 Recombinant Rabbit Monoclonal Antibody [JE51-72] used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.