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Product details

PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59]

Catalog number ET7110-20

Price for ET7110-20

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Size / count 100 µL

About this product

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.

Specifications

Catalog number
ET7110-20
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
HC8 antibody Macropain subunit C8 antibody MGC12306 antibody MGC32631 antibody Multicatalytic endopeptidase complex subunit C8 antibody Proteasome (prosome macropain) subunit alpha type 3 antibody Proteasome alpha 3 subunit antibody Proteasome component C8 antibody Proteasome subunit alpha type 3 antibody Proteasome subunit alpha type-3 antibody Proteasome subunit C8 antibody PSA3_HUMAN antibody PSC8 antibody psmA3 antibody
Abbreviation
PSMA3
Swiss Prot
P25788 Human, O70435 Mouse, P18422 Rat
Cellular Locus
Cytoplasm, Nucleus, Proteasome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human PSMA3 aa 1-189 / 255.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
A549 cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, SW620, rat large intestine tissue, human liver tissue, human breast tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 28 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59]?

The catalog number for PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59] is ET7110-20.

What sizes are available for PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59]?

PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59] is available in the following size(s): 100 µL.

Is PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59] in stock?

PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PSMA3 Recombinant Rabbit Monoclonal Antibody [JE51-59] used for?

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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