WRN Recombinant Rabbit Monoclonal Antibody [JE52-72]

Catalog number ET7110-26

Price for ET7110-26

Size / count 100 µL

About this product

Multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions. May play an important role in the dissociation of joint DNA molecules that can arise as products of homologous recombination, at stalled replication forks or during DNA repair. Alleviates stalling of DNA polymerases at the site of DNA lesions. Important for genomic integrity. Plays a role in the formation of DNA replication focal centers; stably associates with foci elements generating binding sites for RP-A (By similarity). Plays a role in double-strand break repair after gamma-irradiation.

Specifications

Catalog number: ET7110-26
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: DKFZp686C2056 antibody DNA helicase antibody DNA helicase, RecQ like type 3 antibody Exonuclease WRN antibody HGNC 12791 antibody OTTHUMP00000225301 antibody RecQ protein-like 2 antibody RecQ-like type 3 antibody RecQ3 antibody RECQL2 antibody RECQL3 antibody Werner syndrome ATP-dependent helicase antibody Werner syndrome helicase antibody Werner syndrome protein antibody Werner syndrome, RecQ helicase like antibody WRN antibody WRN_HUMAN antibody
Abbreviation: WRN
Swiss Prot: Q14191 Human
Cellular Locus: Nucleolus, nucleus, nucleoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human WRN aa 1,260-1,432 / 1,432.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: HeLa cell lysate, Jurkat cell lysate, K-562 cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 162 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for WRN Recombinant Rabbit Monoclonal Antibody [JE52-72]?

The catalog number for WRN Recombinant Rabbit Monoclonal Antibody [JE52-72] is ET7110-26.

What sizes are available for WRN Recombinant Rabbit Monoclonal Antibody [JE52-72]?

WRN Recombinant Rabbit Monoclonal Antibody [JE52-72] is available in the following size(s): 100 µL.

Is WRN Recombinant Rabbit Monoclonal Antibody [JE52-72] in stock?

WRN Recombinant Rabbit Monoclonal Antibody [JE52-72] is currently made to order / not held in immediate stock. Contact us for lead time.

What is WRN Recombinant Rabbit Monoclonal Antibody [JE52-72] used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.