ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36] — image 1 of 3

Product details

ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36]

Catalog number ET7110-29

Price for ET7110-29

Size / count 100 µL

About this product

The endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1) is localized to the lumen of the ER, which removes NH2-terminal residues from many antigenic precursors for MHC class I peptide presentation. ERAP1 is also designated adipocyte-derived leucine aminopeptidase (A-LAP), puromycin-insensitive leucine-specific aminopeptidase (PILS-AP) and aminopeptidase regulator of TNFR1 shedding (ARTS-1). Peptides presented by MHC class I on the surface of a cell must be eight to eleven residues long and ERAP1 specifically trims peptides of nine amino acids or more. ERAP1 is induced by interferon-g and encoded for by the ARTS1 gene, which maps to human chromosome 5q15. ERAP1 is thought to inactivate several bioactive peptides, including angioten-sin II, and subsequently, may be involved in the regulation of blood pressure. It may have a role in angiogenesis by regulating the proliferation and migration of endothelial cells, and is characterized as a TNFR1 binding protein that promotes TNFR1 shedding.

Specifications

Catalog number: ET7110-29
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: A LAP antibody A-LAP antibody Adipocyte derived leucine aminopeptidase antibody Adipocyte-derived leucine aminopeptidase antibody ALAP antibody Aminopeptidase PILS antibody Aminopeptidase regulator of TNFR1 shedding antibody APPILS antibody ARTS 1 antibody ARTS-1 antibody Arts1 antibody Endoplasmic reticulum aminopeptidase 1 antibody Endoplasmic reticulum aminopeptidase associated with antigen processing antibody ERAAP antibody ERAAP1 antibody ERAP 1 antibody Erap1 antibody ERAP1_HUMAN antibody KIAA0525 antibody kiaa0525 protein antibody PILS AP antibody PILS-AP antibody PILSA antibody PILSAP antibody Puromycin insensitive leucyl specific aminopeptidase antibody Puromycin-insensitive leucyl-specific aminopeptidase antibody Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody VEGF-induced aminopeptidase antibody
Abbreviation: ERAP1
Swiss Prot: Q9NZ08 Human, Q9JJ22 Rat
Cellular Locus: Endoplasmic reticulum membrane.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within Human ERAP1 aa 833-941 / 941.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Human skin tissue lysates, 293T cell lysates, rat bladder tissue, human small intestine tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:100-1:400
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 107 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36]?

The catalog number for ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36] is ET7110-29.

What sizes are available for ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36]?

ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36] is available in the following size(s): 100 µL.

Is ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36] in stock?

ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ERAP1 Recombinant Rabbit Monoclonal Antibody [JE52-36] used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.