ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17] — image 1 of 3

Product details

ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17]

Catalog number ET7110-41

Price for ET7110-41

Size / count 100 µL

About this product

ECM1 (extracellular matrix protein 1), also known as secretory component p85, is a secreted glycoprotein that is essential for the proper structure and function of the skin. It is widely expressed and localizes to the extracellular matrix. ECM1 binds to a variety of extracellular matrix components, including Perlecan, Fibulin and matrix metalloproteinase-9 (MMP-9), and participates in the structural organization of the dermis. In addition, ECM1 enhances the association of Collagen Type IV with Laminin 332 suggesting that it is a key player in interstitial dermis and the dermal-epidermal junction. Mutations in the gene encoding ECM1 result in the autosomal recessive disorder lipoid proteinosis (LiP). LiP is characterized by hyalinization of the dermis and reduplication of the basement membrane of the skin. LiP patients exhibit thickening of the skin and mucosae. Four splice variants (known as ECM1a-ECM1d) exist for ECM1.

Specifications

Catalog number: ET7110-41
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: ECM 1 antibody Ecm1 antibody ECM1_HUMAN antibody Extracellular matrix protein 1 antibody Secretory component p85 antibody URBWD antibody
Abbreviation: ECM1
Swiss Prot: Q16610 Human, Q62894 Rat
Cellular Locus: extracellular matrix
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within Human ECM1 aa 81-232 / 540.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Rat heart tissue lysates, MCF-7, SiHa, human esophagus tissue.
Concentration: 1 mg/mL
Dilution: WB:1:1,000-1:5,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 61 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17]?

The catalog number for ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17] is ET7110-41.

What sizes are available for ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17]?

ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17] is available in the following size(s): 100 µL.

Is ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17] in stock?

ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ECM1 Recombinant Rabbit Monoclonal Antibody [JE54-17] used for?

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.