ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89] — image 1 of 3

Product details

ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89]

Catalog number ET7110-42

Price for ET7110-42

Size / count 100 µL

About this product

Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation. Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (By similarity). In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (By similarity). Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (By similarity). Also required for nascent adherens junction assembly in epithelial cells.

Specifications

Catalog number: ET7110-42
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Abelson interactor 2 antibody ABI 2 antibody Abi-2 antibody ABI2 antibody ABI2_HUMAN antibody ABI2B antibody Abl binding protein 3 antibody Abl interacting protein 1 (SH3 containing protein) antibody Abl interactor 2 antibody Abl interactor protein 2b antibody Abl-binding protein 3 antibody AblBP3 antibody AIP 1 antibody Arg binding protein 1 antibody Arg protein tyrosine kinase binding protein antibody Arg-binding protein 1 antibody ArgBP1 antibody ARGBPIA antibody ArgBPIB antibody OTTHUMP00000163783 antibody OTTHUMP00000163784 antibody OTTHUMP00000206182 antibody OTTHUMP00000206183 antibody OTTHUMP00000206184 antibody OTTHUMP00000206185 antibody SSH3BP2 antibody
Abbreviation: ABI2
Swiss Prot: Q9NYB9 Human, P62484 Mouse
Cellular Locus: Cell junction, Cell projection, Cytoplasm, Cytoskeleton, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human ABI2 aa 312-411 / 513.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: MCF-7 cell lysates, human lung tissue, mouse testis tissue.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000 ;IHC-P:1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 56 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89]?

The catalog number for ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89] is ET7110-42.

What sizes are available for ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89]?

ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89] is available in the following size(s): 100 µL.

Is ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89] in stock?

ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ABI2 Recombinant Rabbit Monoclonal Antibody [JE53-89] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.