- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![Neurocan Recombinant Rabbit Monoclonal Antibody [JE54-15] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea81e56/imageurl/et7110-59.webp)
Product details
Catalog number ET7110-59
Price for ET7110-59
Size / count 100 µL
Neurocan core protein is a protein that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and migration. Neurocan is a significant component of the extracellular matrix, and its levels are modulated by a variety of factors, but mice in which the NCAN gene has been knocked out show no easily observable defects in brain development or behavior. However, a genome-wide association study published in 2011 identified Neurocan as a susceptibility factor for bipolar disorder. A more comprehensive study published in 2012 confirmed that association. The 2012 study examined correlations between NCAN alleles and various symptoms of bipolar disorder, and also examined the behavior of NCAN knockout mice. In the human subjects, it was found that NCAN genotype was strongly associated with manic symptoms but not with depressive symptoms. In the mice, the absence of functional Neurocan resulted in a variety of manic-like behaviors, which could be normalized by administering lithium.
The catalog number for Neurocan Recombinant Rabbit Monoclonal Antibody [JE54-15] is ET7110-59.
Neurocan Recombinant Rabbit Monoclonal Antibody [JE54-15] is available in the following size(s): 100 µL.
Neurocan Recombinant Rabbit Monoclonal Antibody [JE54-15] is currently made to order / not held in immediate stock. Contact us for lead time.
Neurocan core protein is a protein that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and m
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.
We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.
