RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53] — image 1 of 2

Product details

RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53]

Catalog number ET7110-65

Price for ET7110-65

Size / count 100 µL

About this product

Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP. Impaired autophagic degradation of lncRNA ARHGAP5-AS1 in chemoresistant cancer cells promoted chemoresistance. It can activate the transcription of ARHGAP5 in the nucleus and stimulate m6A modification of ARHGAP5 mRNA to stabilize ARHGAP5 mRNA in the cytoplasm by recruiting METTL3. Therefore, targeting ARHGAP5-AS1/ARHGAP5 axis might be a promising strategy to overcome chemoresistance in gastric cancer.

Specifications

Catalog number: ET7110-65
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: ARHGAP 5 antibody ARHGAP5 antibody p190 B antibody p190 RhoGAP antibody Rho GTPase activating protein 5 antibody RhoGAP 5 antibody RhoGAP antibody RhoGAP5 antibody
Abbreviation: ARHGAP5
Swiss Prot: Q13017 Human, P97393 Mouse,
Cellular Locus: Cell membrane, cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human ARHGAP5 aa 1,130-1,320 / 1,502.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, FC
Positive Control: NIH/3T3 cell lysate, PC-12 cell lysate, SiHa cell lysate, HepG2 cell lysate, SiHa.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000 ;FC:1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 172 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53]?

The catalog number for RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53] is ET7110-65.

What sizes are available for RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53]?

RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53] is available in the following size(s): 100 µL.

Is RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53] in stock?

RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53] is currently made to order / not held in immediate stock. Contact us for lead time.

What is RhoGAP Recombinant Rabbit Monoclonal Antibody [JE53-53] used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.