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Product details

CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35]

Catalog number ET7110-67

Price for ET7110-67

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Size / count 100 µL

About this product

Charged multivesicular body protein 2b is a protein that in humans is encoded by the CHMP2B gene.It forms part of one of the endosomal sorting complexes required for transport (ESCRT) - specifically ESCRT-III - which are a series of complexes involved in cell membrane remodelling. CHMP2B forms long chains that spiral around the neck of a budding vesicle. Along with the other components of ESCRT-III, CHMP2B constricts the neck of the vesicle just before it is cleaved away from the membrane. Mutations of this gene cause chromosome 3-linked frontotemporal dementia (FTD3), which has been described in several members of one Danish family . In a study of French families with several forms of frontotemporal dementia, it was found to be a relatively rare cause.

Specifications

Catalog number
ET7110-67
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ALS17 antibody Charged multivesicular body protein 2b antibody CHM2B_HUMAN antibody CHMP family, member 2B antibody CHMP2.5 antibody CHMP2b antibody Chromatin modifying protein 2b antibody Chromatin-modifying protein 2b antibody hVps2-2 antibody Vacuolar protein sorting 2, yeast, homolog of, B antibody Vacuolar protein sorting 2-2 antibody Vacuolar protein sorting-associated protein 2-2 antibody VPS2 homolog B antibody Vps2-2 antibody VPS2B antibody
Abbreviation
CHMP2B
Swiss Prot
Q9UQN3 Human, Q8BJF9 Mouse
Cellular Locus
Late endosome membrane, cytosol.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human CHMP2B aa 103-213 / 213.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Mouse bone marrow tissue lysate, rat bone marrow tissue lysate, human skeletal muscle tissue lysate, A549 cell lysate, A431 cell lysate, Hela cell lysate, SW620, SW1990, mouse testis tissue, mouse kidney tissue, A549.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200;FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 24 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35]?

The catalog number for CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35] is ET7110-67.

What sizes are available for CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35]?

CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35] is available in the following size(s): 100 µL.

Is CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35] in stock?

CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CHMP2B Recombinant Rabbit Monoclonal Antibody [JE54-35] used for?

Charged multivesicular body protein 2b is a protein that in humans is encoded by the CHMP2B gene.It forms part of one of the endosomal sorting complexes required for transport (ESCRT) - specifically ESCRT-III - which are a series of complexes involved in cell membrane remodelling. CHMP2B forms long

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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