RPL7A Recombinant Rabbit Monoclonal Antibody [JE54-45]

About this product

60S ribosomal protein L7a is a protein that in humans is encoded by the RPL7A gene.Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Specifications

Catalog number

ET7110-70

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

60S ribosomal protein L7a antibody L7A antibody MGC103146 antibody PLA X polypeptide antibody PLA-X polypeptide antibody ribosomal protein L7a antibody RL7A_HUMAN antibody RP23-414L19.4 antibody RPL7A antibody SURF 3 antibody SURF-3 antibody SURF3 antibody surfeit 3 antibody Surfeit locus protein 3 antibody Thyroid hormone receptor uncoupling protein antibody TRUP antibody

Abbreviation

RPL7A

Swiss Prot

P62424 Human, P12970 Mouse

Cellular Locus

Cytosol, cytosolic large ribosomal subunit, nucleolus, nucleus, cytoplasm, focal adhesion, membrane, polysomal ribosome, synapse.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant protein within Human RPL7A aa 1-165 / 266.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

A431 cell lysate, Jurkat cell lysate, Raji cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB:1:500-1:1,000 ;IHC-P:1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

30 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes