DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52]

Catalog number ET7110-75

Price for ET7110-75

Size / count 100 µL

About this product

Docking protein 1 is a protein that in humans is encoded by the DOK1 gene. The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Several transcript variants encoding different isoforms have been found for this gene. Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

Specifications

Catalog number: ET7110-75
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Docking protein 1 62kD antibody Docking protein 1 antibody DOK 1 antibody DOK1 antibody DOK1_HUMAN antibody Downstream of tyrosine kinase 1 antibody p62 (dok) antibody P62DOK antibody pp62 antibody
Abbreviation: DOK1
Swiss Prot: Q99704 Human, Q4QQV2 Rat, P97465 Mouse
Cellular Locus: Nucleus, cytoplasm; Perinuclear region.
Host: Rabbit
Species Reactivity: Human, Rat, Mouse
Immunogen: Recombinant protein within Human DOK1 aa 360-481 / 481.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: K562 cell lysate, rat skin tissue lysate, mouse pancreas tissue lysates.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 19/37/52 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52]?

The catalog number for DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52] is ET7110-75.

What sizes are available for DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52]?

DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52] is available in the following size(s): 100 µL.

Is DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52] in stock?

DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DOK1 Recombinant Rabbit Monoclonal Antibody [JE54-52] used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.