NFYA Recombinant Rabbit Monoclonal Antibody [JE54-87]

About this product

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Specifications

Catalog number

ET7110-85

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CAAT box DNA binding protein subunit A antibody CAAT box DNA-binding protein subunit A antibody CBF A antibody CBF B antibody CBFA antibody CBFB antibody CCAAT binding transcription factor subunit B antibody FLJ11236 antibody HAP 2 antibody HAP2 antibody HAP2 CCAAT binding protein antibody NF YA antibody NF-YA antibody NFY protein chain A antibody NFYA antibody NFYA_HUMAN antibody NUCLEAR FACTOR BINDING TO Y BOX OF HLA GENES antibody Nuclear transcription factor Y alpha antibody Nuclear transcription factor Y antibody Nuclear transcription factor Y subunit A antibody Nuclear transcription factor Y subunit alpha antibody Sez10 antibody Transcription factor NF Y A subunit antibody

Abbreviation

NFYA

Swiss Prot

P23511 Human, P23708 Mouse, P18576 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human NFYA aa 298-347 / 347.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

293T cell lysate, HepG2 cell lysate, rat large intestine tissue, mouse kidney tissue, rat testis tissue, human skin tissue, human breast tissue, human colon carcinoma tissue, human prostate carcinoma tissue, mouse liver tissue, THP-1, rat colon tissue.

Concentration

1 mg/mL

Dilution

WB:1:500-1:2,000 ;IHC-P:1:100-1:1,000 ;FC:1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size:34/37 Da.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes