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![Kallikrein 5 Recombinant Rabbit Monoclonal Antibody [JE54-94] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea82568/imageurl/et7110-90.webp)
Product details
Catalog number ET7110-90
Price for ET7110-90
Size / count 100 µL
Kallikrein-related peptidase 5 (KLK5), formerly known as stratum corneum tryptic enzyme (SCTE), is a serine protease expressed in the epidermis. In humans it is encoded by the KLK5 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. Alternative splicing results in multiple transcript variants encoding the same protein. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.
The catalog number for Kallikrein 5 Recombinant Rabbit Monoclonal Antibody [JE54-94] is ET7110-90.
Kallikrein 5 Recombinant Rabbit Monoclonal Antibody [JE54-94] is available in the following size(s): 100 µL.
Kallikrein 5 Recombinant Rabbit Monoclonal Antibody [JE54-94] is currently made to order / not held in immediate stock. Contact us for lead time.
Kallikrein-related peptidase 5 (KLK5), formerly known as stratum corneum tryptic enzyme (SCTE), is a serine protease expressed in the epidermis. In humans it is encoded by the KLK5 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expressio
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
