- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![TEAD1 Recombinant Rabbit Monoclonal Antibody [JE52-71] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81815/imageurl/et7111-04.webp)
Product details
Catalog number ET7111-04
Price for ET7111-04
Size / count 100 µL
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
The catalog number for TEAD1 Recombinant Rabbit Monoclonal Antibody [JE52-71] is ET7111-04.
TEAD1 Recombinant Rabbit Monoclonal Antibody [JE52-71] is available in the following size(s): 100 µL.
TEAD1 Recombinant Rabbit Monoclonal Antibody [JE52-71] is currently made to order / not held in immediate stock. Contact us for lead time.
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
