Desmocollin 3 Recombinant Rabbit Monoclonal Antibody [JE55-86]

About this product

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Specifications

Catalog number

ET7111-26

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Cadherin family member 3 antibody CDHF3 antibody desmocollin 3a/3b antibody Desmocollin 4 antibody Desmocollin-3 antibody Desmocollin-4 antibody Desmocollin3 antibody Desmocollin4 antibody DSC antibody DSC1 antibody DSC2 antibody DSC3 antibody DSC3_HUMAN antibody DSC4 antibody HT CP antibody HT-CP antibody HTCP antibody

Abbreviation

DSC3

Swiss Prot

Q14574 Human, P55850 Mouse,

Cellular Locus

Cell membrane, desmosome.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within C-terminal Human Desmocollin 3.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

A431 cell lysate, HCT 116 cell lysate, mouse skin tissue lysate, rat skin tissue lysate, 293T, human skin tissue, mouse esophagus tissue, A431.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 100 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes