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Product details

PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36]

Catalog number ET7111-33

Price for ET7111-33

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Size / count 100 µL

About this product

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number
ET7111-33
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Alpha PAK antibody Alpha-PAK antibody MGC130000 antibody MGC130001 antibody p21 activated kinase 1 antibody p21 protein (Cdc42/Rac) activated kinase 1 antibody p21-activated kinase 1 antibody p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) antibody p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) antibody p65 PAK antibody p65-PAK antibody P68-PAK antibody PAK alpha antibody PAK-1 antibody Pak1 antibody PAK1_HUMAN antibody Paka antibody PAKalpha antibody Protein kinase MUK2 antibody Rac/p21-activated kinase antibody Serine/threonine-protein kinase PAK 1 antibody STE20 homolog yeast antibody
Abbreviation
PAK1
Swiss Prot
Q13153 Human, O88643 Mouse, P35465 Rat
Cellular Locus
Nucleoplasm, Cell membrane, ruffle membrane, Cytoplasm, focal adhesion, invadopodium, Chromosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Rat
Immunogen
Synthetic peptide within human PAK1 aa 1-50.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
HL-60 cell lysates, F9, human lung carcinoma tissue, human stomach carcinoma tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
61 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36]?

The catalog number for PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36] is ET7111-33.

What sizes are available for PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36]?

PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36] is available in the following size(s): 100 µL.

Is PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36] in stock?

PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PAK1 Recombinant Rabbit Monoclonal Antibody [JE57-36] used for?

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. Protein ki

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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