Rad51B Rabbit Polyclonal Antibody

Catalog number HA500010

Price for HA500010

Size / count 100 µL

About this product

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.

Specifications

Catalog number: HA500010
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: DNA repair protein RAD51 homolog 2 antibody hREC2 antibody MGC34245 antibody OTTHUMP00000212251 antibody OTTHUMP00000212253 antibody OTTHUMP00000212254 antibody OTTHUMP00000212255 antibody R51H2 antibody RA51B_HUMAN antibody RAD51 homolog B (S. cerevisiae) antibody RAD51 homolog B antibody RAD51 like 1 antibody RAD51 like protein 1 antibody RAD51-like protein 1 antibody Rad51B antibody RAD51L1 antibody REC2 antibody RecA like protein antibody Recombination repair protein antibody
Abbreviation: R51H2 Rad51B RAD51L1 REC2
Swiss Prot: O15315 Human
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within C-terminal human Rad51B.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, FC
Positive Control: SKBR3 cell lysate, PC-12 cell lysate, SiHa.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;FC: 1:500-1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 42 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Rad51B Rabbit Polyclonal Antibody?

The catalog number for Rad51B Rabbit Polyclonal Antibody is HA500010.

What sizes are available for Rad51B Rabbit Polyclonal Antibody?

Rad51B Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Rad51B Rabbit Polyclonal Antibody in stock?

Rad51B Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Rad51B Rabbit Polyclonal Antibody used for?

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.