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Product details

MAT2A Rabbit Polyclonal Antibody

Catalog number HA500028

Price for HA500028

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Size / count 100 µL

About this product

Protein expression is regulated by post-transcriptional regulation: in presence of S-adenosyl-L-methionine, METTL16 binds and methylates the first hairpin of the 3'-UTR region of MAT2A mRNA, impairing MAT2A expression . In S-adenosyl-L-methionine-limiting conditions, METTL16 binds the 3'-UTR region of MAT2A mRNA without methylating it due to the lack of a methyl donor, preventing N6-methylation and promoting expression of MAT2A . Consequences of N6-methylation of MAT2A are however subject to discussion: According to a report, N6-methylation of MAT2A affects MAT2A mRNA splicing ). According to a second report, N6-methylation of MAT2A affects MAT2A mRNA stability (By similarity).By similarity1 Publication.

Specifications

Catalog number
HA500028
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
AdoMet synthase 2 antibody AdoMet synthetase 2 antibody AdoMet synthetase antibody AMS 2 antibody AMS2 antibody MAT 2 antibody MAT 2A antibody MAT II antibody MAT-II antibody Mat2a antibody MATA 2 antibody MATA2 antibody MATII antibody Methionine adenosyltransferase 2 antibody Methionine adenosyltransferase antibody Methionine adenosyltransferase II alpha antibody Methionine adenosyltransferase II antibody METK2_HUMAN antibody S adenosylmethionine synthetase gamma form antibody S adenosylmethionine synthetase isoform type 2 antibody S-adenosylmethionine synthase isoform type-2 antibody SAMS 2 antibody SAMS2 antibody
Abbreviation
S-adenosylmethionine synthase isoform type-2 AdoMet synthase 2 Methionine adenosyltransferase 2 MAT 21 Methionine adenosyltransferase II MAT-II
Swiss Prot
P31153 Human, Q3THS6 Mouse, P18298 Rat
Cellular Locus
Nucleoplasm, Cytosol.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human MAT2A aa 70-260.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Rat kidney tissue lysates, rat kidney tissue, human colon tissue, human colon carcinoma tissue, mouse brain tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:500-1:2,000 ;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for MAT2A Rabbit Polyclonal Antibody?

The catalog number for MAT2A Rabbit Polyclonal Antibody is HA500028.

What sizes are available for MAT2A Rabbit Polyclonal Antibody?

MAT2A Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is MAT2A Rabbit Polyclonal Antibody in stock?

MAT2A Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is MAT2A Rabbit Polyclonal Antibody used for?

Protein expression is regulated by post-transcriptional regulation: in presence of S-adenosyl-L-methionine, METTL16 binds and methylates the first hairpin of the 3'-UTR region of MAT2A mRNA, impairing MAT2A expression . In S-adenosyl-L-methionine-limiting conditions, METTL16 binds the 3'-UTR region

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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