NLK Rabbit Polyclonal Antibody — image 1 of 3

Product details

NLK Rabbit Polyclonal Antibody

Catalog number HA500033

Price for HA500033

Size / count 100 µL

About this product

Nlk Antibody (B-5) is a high quality monoclonal Nlk antibody (also designated Nlk antibody) suitable for the detection of the Nlk protein of mouse, rat and human origin. Nlk Antibody (B-5) is available as both the non-conjugated anti-Nlk antibody form, as well as multiple conjugated forms of anti-Nlk antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2 (1-4), respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both Thr 183 and Tyr 185 is required for full enzymatic activation. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine. Nlk, or nemo-like kinase, is a murine homolog of the Drosophila nemo (nmo) gene. Nlk and Nmo have sequence homology to both the ERK MAP kinases and the cyclin dependent kinases. Nlk is a nuclear protein with the ability to autophosphorylate.

Specifications

Catalog number: HA500033
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: DKFZp761G1211 antibody FLJ21033 antibody LAK1 antibody Nemo like kinase antibody Nemo-like kinase antibody Nlk antibody NLK_HUMAN antibody Protein LAK1 antibody Serine/threonine protein kinase NLK antibody Serine/threonine-protein kinase NLK antibody
Abbreviation: NLK
Swiss Prot: Q9UBE8 Human, O54949 Mouse
Cellular Locus: Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within C-terminal human NLK.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: SW480 cell lysate, HCT116 cell lysate, C2C12 cell lysate, MG-63, SW620, human uterus tissue, human small intestine tissue, human breast carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200
Purity: Protein affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 58 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for NLK Rabbit Polyclonal Antibody?

The catalog number for NLK Rabbit Polyclonal Antibody is HA500033.

What sizes are available for NLK Rabbit Polyclonal Antibody?

NLK Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is NLK Rabbit Polyclonal Antibody in stock?

NLK Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is NLK Rabbit Polyclonal Antibody used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.