Gemin 2 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Gemin 2 Rabbit Polyclonal Antibody

Catalog number HA500045

Price for HA500045

Size / count 100 µL

About this product

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Specifications

Catalog number: HA500045
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Component of gems 2 antibody Gem (nuclear organelle) associated protein 2 antibody Gem associated protein 2 antibody GEMI2_HUMAN antibody Gemin-2 antibody gemin2 antibody SIP 1 antibody SIP-1 antibody SIP1 antibody SIP1 delta antibody SIP1-delta antibody SMN interacting protein 1 antibody SMN interacting protein 1 delta antibody SMN-interacting protein 1 antibody Survival interacting protein 1 antibody Survival of motor neuron protein interacting protein 1 antibody Survival of motor neuron protein-interacting protein 1 antibody
Abbreviation: Gem-associated protein 2 Gemin-2 Component of gems 2 Survival of motor neuron protein-interacting protein 1 SMN-interacting protein 1
Swiss Prot: O14893 Human, Q9CQQ4 Mouse
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within human Gemin 2 aa 230-280.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Hela cell lysate, Jurkat cell lysate, 293T cell lysate, mouse kidney tissue lysates, human skeletal muscle tissue, human kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 32 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Gemin 2 Rabbit Polyclonal Antibody?

The catalog number for Gemin 2 Rabbit Polyclonal Antibody is HA500045.

What sizes are available for Gemin 2 Rabbit Polyclonal Antibody?

Gemin 2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Gemin 2 Rabbit Polyclonal Antibody in stock?

Gemin 2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Gemin 2 Rabbit Polyclonal Antibody used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.