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Product details

Munc13-4 Rabbit Polyclonal Antibody

Catalog number HA500052

Price for HA500052

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Size / count 100 µL

About this product

Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca2+-dependent secretory lysosome exocytosis in mast cells.Expressed at high levels in spleen, thymus and leukocytes. Also expressed in lung and placenta, and at very low levels in brain, heart, skeletal muscle and kidney. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.

Specifications

Catalog number
HA500052
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
FHL 3 antibody FHL3 antibody FLJ00067 antibody HLH 3 antibody HLH3 antibody HPLH 3 antibody HPLH3 antibody Jinx antibody Munc13 4 antibody Munc13-4 antibody Protein unc 13 homolog D antibody Protein unc-13 homolog D antibody UN13D_HUMAN antibody Unc 13 homolog D antibody UNC 13D antibody Unc-13 homolog D (C. elegans) antibody Unc13 homolog D (C elegans) antibody Unc13 homolog D antibody UNC13, C. elegans, homolog of, D antibody UNC13D antibody Unc13h4 antibody
Abbreviation
Protein unc-13 homolog D,Munc13-4,NC13D
Swiss Prot
Q70J99 Human, B2RUP2 Mouse, Q9R189 Rat
Cellular Locus
Cytoplasm, Endosome, Lysosome, Membrane.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human Munc13-4 aa 900-1090.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Jurkat cell lysate, K562 cell lysate, rat lung tissue lysate, Hela, SHSY5Y, rat spleen tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
123 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Munc13-4 Rabbit Polyclonal Antibody?

The catalog number for Munc13-4 Rabbit Polyclonal Antibody is HA500052.

What sizes are available for Munc13-4 Rabbit Polyclonal Antibody?

Munc13-4 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Munc13-4 Rabbit Polyclonal Antibody in stock?

Munc13-4 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Munc13-4 Rabbit Polyclonal Antibody used for?

Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with p

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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